Home > leptospirosis, magnesium, renal failure > Hypomagnesemia in Acute Leptospirosis

Hypomagnesemia in Acute Leptospirosis

I have seen this in my canine patients. Have you seen it as well?

Case report: severe, symptomatic hypomagnesemia in acute leptospirosis.

Spichler A, Athanazio DA, Furtado J, Seguro A, Vinetz JM.

We report a case of severe hypomagnesemia in non-oliguric acute renal failure caused by leptospirosis that required large doses of magnesium replacement during the acute phase of disease. Biochemical studies confirmed kidney-related magnesium wasting and the mechanisms of this defect are discussed. Magnesium imbalance with its attendant clinical complications occurs in leptospirosis and should be monitored and treated aggressively in cases of leptospirosis-induced non-oliguric acute kidney injury.

PMCID: PMC2637037
PMID: 19052304 [PubMed – indexed for MEDLINE]

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